What Are PDE5 Inhibitors? (And How They Help ED)

PDE5 inhibitors are a class of drugs designed to treat erectile dysfunction by enhancing blood flow to the penis. They include sildenafil (Viagra), tadalafil (Cialis), and vardenafil (Levitra). These meds relax blood vessels and amplify natural arousal responses.

How They Work

• Block the enzyme PDE5
• Increase nitric oxide levels
• Allow better blood retention in the penis

What to Expect

They don’t create arousal — they support it. Take 30–60 minutes before intercourse. Don’t mix with nitrates or alcohol heavily.

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Disclaimer: Consult your doctor before using PDE5 inhibitors, especially if you have heart issues.